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managing your diabetes.

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helping you lower
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Call The Lilly Answers Center
Call: 1-800-LillyRx (1-800-545-5979)

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You’re committed to managing your diabetes.

Lilly is committed to helping you lower your out-of-pocket costs.

Lilly's Insulin Lispro Injection U-100 is a different-priced mealtime insulin option to Humalog® (insulin lispro injection) U-100 that may help lower out-of-pocket costs.

Just like Humalog, it is a fast-acting insulin that helps control the blood sugar spikes that happen naturally when you eat. Insulin Lispro Injection should be taken 15 minutes before or immediately after a meal. Insulin Lispro Injection is different than your long-acting insulin. Long-acting insulin helps control your blood sugar throughout the whole day.

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Find out if Lilly’s Insulin Lispro Injection is right for you.

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When you go to pick up your prescription, your pharmacist will help evaluate if Humalog or Lilly’s Insulin Lispro Injection is the least expensive option for you.*

*

Important: In some situations, Humalog may still be your least expensive option. Patients should consider formulary status of all medications they may be taking when making enrollment decisions.

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Just as with Humalog, Lilly’s Insulin Lispro Injection is available in the easy-to-use KwikPen® or vial.

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For immediate, personalized assistance on the most affordable option for you, please call the
Lilly Diabetes Solution Center at 1-833-808-1234, Monday through Friday, 9 am-8 pm ET.

Find out if Lilly’s Insulin Lispro Injection is right for you.

pharmacy-icon

When you go to pick up your prescription, your pharmacist will help evaluate if Humalog or Lilly’s Insulin Lispro Injection is the least expensive option for you.*

*

Important: In some situations, Humalog may still be your least expensive option. Patients should consider formulary status of all medications they may be taking when making enrollment decisions.

pen and vial icon

Just as with Humalog, Lilly’s Insulin Lispro Injection is available in the easy-to-use KwikPen® or vial.

telephone icon

For immediate, personalized assistance on the most affordable option for you, please call the Lilly Diabetes Solution Center at 1-833-808-1234, Monday through Friday, 9 am-8 pm ET.

Indication Statement for Humalog Brand of Insulins and Insulin Lispro Injection

Humalog and Insulin Lispro Injection are used to treat people with diabetes for the control of high blood sugar. Humalog Mix75/25 and Humalog Mix50/50 are used to treat adults with diabetes for the control of high blood sugar.

Important Safety Information for Humalog Brand of Insulins and Insulin Lispro Injection

What is the most important information I should know about Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, and Insulin Lispro Injection?

  • Do not share your Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, or Insulin Lispro Injection prefilled pen, cartridges, reusable pen compatible with Lilly 3 mL cartridges, needles, or syringes with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.
  • Do not change the type or amount of insulin you use without talking to your healthcare provider. Changes may make you more likely to experience low or high blood sugar. Changes should be made cautiously under the supervision of your healthcare provider.
  • Check your blood sugar levels as your healthcare provider instructs.
  • The amount of insulin and the best time for you to take your dose may need to change if you take different types of insulin or because of illness, increased stress, other medicines you take, change in diet, weight gain or loss, or change in physical activity or exercise.
  • Humalog U-200 must ONLY be injected with the single-patient-use Humalog U-200 KwikPen. The Humalog U-200 KwikPen contains 2 times as much insulin (200 units/mL) in 1 mL as standard insulin (100 units/mL). Do not withdraw Humalog U-200 from your KwikPen using a syringe. It could result in an overdose causing severe low blood sugar which may put your life in danger.

Who should not take Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, or Insulin Lispro Injection?

  • Do not take these insulins if your blood sugar is too low (hypoglycemia) or if you are allergic to insulin lispro or any of the ingredients in these insulins.

What should I tell my healthcare provider before taking Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50 or Insulin Lispro Injection?

Tell your healthcare provider about all of your medical conditions and all of the medicines you take, including if you:

  • have heart failure or other heart, liver, or kidney problems.
  • are pregnant, breastfeeding, or plan to become pregnant or breastfeed.
  • take medicines commonly called TZDs (thiazolidinediones) or any other prescription or over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50 and Insulin Lispro Injection?

  • Low blood sugar is the most common side effect. Severe low blood sugar may put your life in danger and can cause seizures or death. Signs and symptoms of low blood sugar may be different for each person and may include dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood changes, and hunger. Your healthcare provider may prescribe a glucagon emergency kit if your blood sugar becomes too low and you are unable to take sugar by mouth. Be sure to talk to your healthcare provider about low blood sugar and how to manage it.
  • Severe life-threatening allergic reactions (whole-body reactions) can happen. Get medical help right away if you have: a rash over your whole body, trouble breathing, shortness of breath, a fast heartbeat, swelling of your face, tongue or throat, sweating, extreme drowsiness, dizziness, or confusion or feel faint.
  • Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, and Insulin Lispro Injection can cause life-threatening low potassium in your blood (hypokalemia). This can cause severe breathing problems, irregular heartbeat, and death.
  • Swelling of your hands and feet and heart failure may occur when taking certain pills called thiazolidinediones or “TZDs” with Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, or Insulin Lispro Injection. This can happen in some people even if they have not had heart problems before. Tell your healthcare provider if you have shortness of breath, swelling of your ankles or feet, or sudden weight gain, which may be symptoms of heart failure. Your healthcare provider may need to adjust or stop your treatment with TZDs and Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, or Insulin Lispro Injection.
  • Failure of your insulin pump or infusion set or degradation of the insulin in the pump can cause hyperglycemia and ketoacidosis. Always carry an alternate form of insulin administration in case of pump failure.
  • The most common side effects of Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, and Insulin Lispro Injection include: low blood sugar, allergic reactions, including reactions at your injection site, skin thickening or pits at the injection site (lipodystrophy), weight gain, swelling in your hands or feet, itching, and rash.

These are not all of the possible side effects. Ask your healthcare provider for more information or for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How should I take Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, or Insulin Lispro Injection?

  • Check your insulin label before each injection to make sure you are taking the correct type of insulin.
  • Do not re-use needles. Always use a new needle for each injection. Re-use of needles can cause you to get the wrong dose of insulin or result in a serious infection.
  • These insulins start acting fast. Inject Humalog U-100, Humalog U-200, or Insulin Lispro Injection within fifteen minutes before or right after eating a meal. Inject Humalog Mix75/25 or Humalog Mix50/50 within fifteen minutes before you eat a meal.
  • Inject your insulin under your skin (subcutaneously). Never inject into a vein or muscle.
  • Change (rotate) where you inject your insulin with each dose.  This can reduce your chance of getting pits, lumps, or thickened skin where you inject your insulin. Do not inject your insulin into the exact same spot or where the skin has pits or lumps. Avoid injecting into thickened, tender, bruised, scaly, hard, or damaged skin.   
  • Never mix Humalog U-200, Humalog Mix75/25, or Humalog Mix50/50 with other insulins or liquids. Never use Humalog U-200, Humalog Mix75/25, or Humalog Mix50/50 in a pump.
  • Do not drive or operate heavy machinery until you know how Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, or Insulin Lispro Injection affects you.
  • Do not drink alcohol or take medicines that contain alcohol while taking Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, or Insulin Lispro Injection.

Humalog U-100, Humalog U-200, Humalog Mix75/25, Humalog Mix50/50, and Insulin Lispro Injection are available by prescription only.

For additional information talk to your healthcare providers and please click to access Humalog Full Prescribing Information, Humalog U-100 Patient Prescribing Information, Humalog U-200 Patient Prescribing Information, Humalog Mix75/25 Full Prescribing Information, Humalog Mix75/25 Patient Prescribing Information, Humalog Mix50/50 Full Prescribing Information, Humalog Mix50/50 Patient Prescribing Information, Insulin Lispro Injection Full Prescribing Information, and Insulin Lispro Injection Patient Prescribing Information

Please see Humalog U-100 KwikPen Instructions for Use / Humalog Junior KwikPen Instructions for Use / Humalog U-100 Vial Instructions for Use / Humalog U-200 KwikPen Instructions for Use / Humalog Mix75/25 KwikPen Instructions for Use / Humalog Mix75/25 Vial Instructions for Use / Humalog Mix50/50 KwikPen Instructions for Use / Humalog Mix50/50 Vial Instructions for Use / Insulin Lispro Injection KwikPen Instructions for Use / Insulin Lispro Injection Vial Instructions for Use included with your pen.

HI BOI SP CON ISI 15NOV2019

Humalog® and KwikPen® are registered trademarks of Eli Lilly and Company, its subsidiaries, or affiliates, and are available by prescription only.